독일 일반 면세 구매대행
임시 중단 안내
안녕하세요. 오마이집입니다.
더 나은 서비스를 위해
독일 일반 면세 구매대행 서비스를 임시 중단합니다.
새로운 모습으로 빠른 시일 내 다시 인사드리겠습니다.
감사합니다.
US
DE
498 Centerpoint Blvd
[사서함번호]
New Castle, DE, 19720
302-322-8792
* 항공운송만 가능
US
CA
2601 Walnut Ave
[사서함번호]
Tustin, CA, 92780
714-676-7274
* 해상운송만 가능
China
山东省威海市 环翠区 苘山镇
福州路9号 顺丰速递北20米
[사서함번호]
264414
156-8451-3564
* 항공&해상운송 가능
Germany
WarpEx [사서함번호]
Carl-Benz Str. 35
Frankfurt am Main, Hessen, Deutschland
60386
0614-2482-9236
* 항공운송만 가능
Korea
서울시 강서구 마곡중앙6로 11 보타닉파크타워3 405호
[사서함번호]
07801
070-5228-2983
Japan
福岡県 福岡市東区
和白東1丁目16-15 HANIRO
[사서함번호]
811-0214
092-608-7642
* 해상운송만 가능
고객센터 알림
NO | 안내시간 | 수취인명 | 신청서번호 | 알림내용 |
---|
* 알림 내용을 클릭하면 해당 페이지로 이동합니다.
Delaware
$36.00
책 정보
출판사 | Independent Aurthor |
---|---|
저자 | Gupta Vivek |
판형 | Paperback |
ISBN-10 | 1805450719 |
ISBN-13 | 9781805450719 |
발행일 | 2022/11/13 |
언어 | eng |
무게 (LB) | 0.72 |
주제 분류
책 소개
Some of the drugs are having very short half-life, to compensate this problem it is common practice to increase the dosage, frequency or prolongation of administration of drug to maintain effective therapeutic concentration in patient. In this study a drug delivery scaffold was designed and synthesized based on polyethylene glycol (PEG)- ethylene diamine tetra acetic acid (EDTA) based poly(amidoamine) (PAMAM) star polymer (with 16 primary amine group on surface). Cloxacillin, Cephalexin and Ciprofloxacin were used as a model drugs having short half life to conjugate with PEGylated dendrimer. These drugs were coupled to star polymer via ester bond. Fourier transform infrared spectroscopy (FT-IR) and proton nuclear magnetic resonance (1 HNMR) was used to characterize the intermediate and drug-star-polymer conjugates. Invitro activity of derivatized drugs compared to standard drug alone, it was found that zone of inhibition obtained by both category of drugs (standard and derivatized drugs) are almost similar. That means drug derivatization does not altering the antibacterial activity of drugs. To investigate pharmacokinetic parameters, selected drugs alone and modified drugs [(Drug-PEG)16-Dendrimer] were intravenously injected into rats. All the modified drugs demonstrated a dramatic increase in half-life than drugs alone. These studies suggest the use of these new PEG based EDTA core dendrimer support as a valuable alternative for enhancing biological half-life of drugs.
트래킹 도착 조회
조회
조회 결과가 없는 경우, 센터로 상품이 도착하지 않은 것이니 판매처로 문의해주시기 바랍니다.
배송신청서에 이미 입고처리가 된 건이나 미작성 입고로 안내된 건은 조회가 되지 않습니다.